The Annotated Research Context (ARC) is a conceptual combination of experimental data with associated annotation, metadata and description of computational workflows. It aims both as structuring the workflows on the local desktop of the user, allow for sharing and versioning and finally be the base of a data publication. The ARC covers the complete research cycle and includes experiment data described with the ISA model, reference knowledge, computational steps like software, code and scripts as information for the core data repositories on transcriptomics, proteomics, metabolomics and phenomics. In DataPLANT the ARCs will be the generic interface for compute and storage as well as publication and sharing.